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Quantitative
Lung Imaging
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A focus of the Quantitative Imaging Laboratory is development and application of quantitative measures for lung assessment in CT images.
Goals of QIA Approach QIA involves computer-assisted techniques for Quantitative Image Analysis of the lung from CT for early diagnosis, stratification of patients and outcome assessment [Gold02a, Brow99b, McNi97a]. Its advantages over lavage and conventional pulmonary function tests (PFTs) are that it is minimally-invasive and able to perform both global and regional assessment of the lung, thus providing greater sensitivity. The QIA technique uses protocols that encompass image acquisition parameters, image processing and statistical analysis. Quantitative Image Data Extraction The QIA package allows a variety of validated quantitative measures to be derived from any segmented lung region or subregion (e.g. anterior, middle or posterior zone, central or peripheral zone and combination zones such as posterior peripheral, middle peripheral, etc.). There are three broad classes of measurements: attenuation statistics; gray-level texture measures; shape and size measures. |
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